Similarities Between Nicotinic and Muscarinic Receptors

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  • Both nicotinic and muscarinic receptors are cholinergic receptors muscarinic receptors.
  • Both nicotinic and muscarinic receptors respond to the neurotransmitter acetylcholine.
  • Nicotinic and muscarinic receptors are found on postganglionic neurons of both the sympathetic and parasympathetic nervous systems.
  • Following agonist binding, both nicotinic and muscarinic receptors undergo conformational changes.
  • Nicotinic and muscarinic receptors also respond to other molecules.

Difference Between Nicotinic and Muscarinic Receptors Compare the Difference Between Similar Terms

definition

Nicotinic Receptors: Nicotinic receptors refer to a group of cholinergic receptors linked to ion channels in the cell membrane.

Muscarinic Receptors: Muscarinic receptors refer to a group of G protein-coupled cholinergic receptors that phosphorylate second messengers.

type

Nicotinic Receptors: The two nicotinic receptors are N1 and N2.

Muscarinic Receptors: The five types of muscarinic receptors are M1, M2, M3, M4 and M5.

excitation/inhibition

Nicotinic Receptors: Nicotinic receptors are excitatory receptors.

Muscarinic Receptors: M1, M2 and M5 are excitatory receptors while M3 and M4 are inhibitory receptors.

occur

Nicotinic Receptors: N1 receptors are present in the neuromuscular junction. N2 receptors are found in the brain, autonomic and parasympathetic nervous systems.

Muscarinic Receptors: Muscarinic receptors are found in the brain, heart and smooth muscle